Finally,
scientists have strong evidence to the validity of the belief that too
much use of antibiotics without the need leads to the emergence of
microbes resistant to these drugs.
Says study author Dr. Herman Goossens, published in The Lancet medical English, "has a lot of studies linking the use of antibiotics and resistant microbes. However, all these studies based on indirect evidence. This study is the first to demonstrate directly that the use of antibiotics vital leads to the emergence of resistance. "
The researchers from the University Hospital Antwerp in Belgium have conducted this study under the leadership of Goossens, who works as a professor of Microbiology.
The study showed that antibiotics have a significant impact on the natural microbial flora such as the various antibiotics which follow the same family have different effects on the bacteria the body.
In the study were recruited healthy volunteers and give them different antibiotics such as Aloztheromitin or Alclaritomitin which follow in the family of anti-Almacrolad third group gave medicines and fake.
The researchers examined the volunteers on a regular basis to observe the effect of the use of antibiotics on the resistance of Streptococcus bacteria.
As expected, the researchers found that levels of resistance rose in the team that gave Aloztheromitin by 50% after eight days of use, meanwhile, rose by more than 53% of the team did not score Alclaritomitin with the team that did not take any antibiotics rise.
While the increased Aloztheromitin of microbial resistance in the short term it seemed that Alclaritomitin ineffective in dealing with bacteria carrying a gene called May or which show considerable resistance to the family of Almacrolad.
It also seemed that the antibiotics affected the harmless bacteria in the mouth and this effect continued after the passage of 180 days.
Goossens said that other studies showed that the spread of resistance genes between bacteria, causing problems such as inflammation of the ear and throat. This can cause difficulty in treating such problems.
According to the researchers, the study concludes that doctors should take into account that the antibiotics long-term effects before prescribing drugs to patients.
However, the difference in the way the resistance of bacteria to antibiotics of different makes it necessary to conduct more research.
Says Dr. Stephanie Dancer in the companion article that the results of the study fills a void with respect to the knowledge of diseases and antibiotics.
"We now have direct evidence on the above, that was just a belief. This is what we need him."
Dancer says: "I have great conviction that antibiotics are effective on the verge of running out."
Says study author Dr. Herman Goossens, published in The Lancet medical English, "has a lot of studies linking the use of antibiotics and resistant microbes. However, all these studies based on indirect evidence. This study is the first to demonstrate directly that the use of antibiotics vital leads to the emergence of resistance. "
The researchers from the University Hospital Antwerp in Belgium have conducted this study under the leadership of Goossens, who works as a professor of Microbiology.
The study showed that antibiotics have a significant impact on the natural microbial flora such as the various antibiotics which follow the same family have different effects on the bacteria the body.
In the study were recruited healthy volunteers and give them different antibiotics such as Aloztheromitin or Alclaritomitin which follow in the family of anti-Almacrolad third group gave medicines and fake.
The researchers examined the volunteers on a regular basis to observe the effect of the use of antibiotics on the resistance of Streptococcus bacteria.
As expected, the researchers found that levels of resistance rose in the team that gave Aloztheromitin by 50% after eight days of use, meanwhile, rose by more than 53% of the team did not score Alclaritomitin with the team that did not take any antibiotics rise.
While the increased Aloztheromitin of microbial resistance in the short term it seemed that Alclaritomitin ineffective in dealing with bacteria carrying a gene called May or which show considerable resistance to the family of Almacrolad.
It also seemed that the antibiotics affected the harmless bacteria in the mouth and this effect continued after the passage of 180 days.
Goossens said that other studies showed that the spread of resistance genes between bacteria, causing problems such as inflammation of the ear and throat. This can cause difficulty in treating such problems.
According to the researchers, the study concludes that doctors should take into account that the antibiotics long-term effects before prescribing drugs to patients.
However, the difference in the way the resistance of bacteria to antibiotics of different makes it necessary to conduct more research.
Says Dr. Stephanie Dancer in the companion article that the results of the study fills a void with respect to the knowledge of diseases and antibiotics.
"We now have direct evidence on the above, that was just a belief. This is what we need him."
Dancer says: "I have great conviction that antibiotics are effective on the verge of running out."
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