Range
from the total amount of iron in the body of the newborn a newborn is
between (1/2 - 1) g, while the adults in this quantity between (4.5 - 5)
g, which is enough to nail industry average size and length. In
order to build a new baby this lack of reserves of iron he does every
day is equivalent to (1 - 1.5) mg of this article, over a period of his
life, and since only ten percent of the iron that reaches the intestine
is absorbed, so it must be Tko n meal food contains any child on the amount of iron not less than (10-15) mg / day.
Iron is absorbed in the medial part of the small intestine proximal, and specifically in the duodenum duodenum and fasting jejunum.
Factors that help to absorb iron are:
Increase the body's need for it.
Acidity of the stomach.
Vitamin C (C c).
While on the contrary, there are factors that reduce absorption are:
Alkaline pancreatic.
Materials and phosphate.
And all the leading cause of injury to the mucosa of the small intestine, especially the duodenum and the jejunum.
Finally, surgery on the stomach and intestines, which reduces surface absorption.
Iron that is absorbed into the blood, the body is distributed in the following places:
Red blood pigment hemoglobin:
It constitutes two thirds iron body almost, so the loss of blood, and for whatever reason, is one of the most important causes of loss of iron, is enough to demonstrate this fact, recall that each (1 cm 3) of the blood containing the (half-mg) of iron, while (1 cm 3) of the red blood cells containing (1 mg) of iron.
Stores of iron stores:
They are of two types:
Stores moving serum ferritin: a special type of protein, carrying iron and was associated with, the average concentration in the blood (35 ng / ml), and the deficiency is considered one of the most important laboratory signs of iron deficiency.
Stores fixed hemosiderin: The distribution in the liver and bone marrow, and the lack or absence of this article from the bone marrow is the most important and earliest signs of iron deficiency anemia as well.
Serum iron serum iron:
And the range of (50-120 mg / dl = 100 ml) in children, and (70-160 mg / dl = 100 ml) in adults.
Yeasts body enzymes:
Iron enters in the composition of many of the enzymes the body so the shortage is reflected in the work of these yeasts, including:
(Catalase, pyroxidase, mono amin oxidase, cytochrome)
Causes of iron deficiency:The most important causes of iron deficiency in the body are:
Blood loss: We have shown and explained a while ago, so is the menstrual cycle in women of the most important causes of anemia for iron deficiency in women.
Lack of iron contained food: where there is abundance of iron in meat, and vegetables with less in the milk it is very poor (the amount of iron not exceeding half mg in a liter of milk of both types of human and bovine).
Defect in the absorption of the duodenum and the fast (see the factors that help or reduce the absorption).
Clinical picture:Tend to show symptoms of iron deficiency anemia in children yen ninth month to the twenty-fourth month of age. Perhaps the most important signs and symptoms of this disease are:
Pallor: a remarkable and Lecco in the mucous membranes of conjunctivitis, and in the lips, hands and in comfort, and the nail bed. If the progress of the disease shall be pale and clear in all parts of the skin.
Poor appetite
Changes in the skin and mucous membranes
Bite the dust
Magnitude of the spleen (10-15% of cases)
Neurological symptoms and signs: and you see in the cases of chronic and non-treatment (such as jittering and neurological).
Laboratory tests:When there is lack of iron in the body, changes occur in a particular sequence, and the first to be affected are:
Stores: Iron pigment decreases in the bone marrow Hemosidrene or disappears completely, and less protein associated with iron in the blood serum to serum ferritin below (10 ng / mL) = 35 ng / ml) n).
Then the blood hematological changes changes
Decreases in serum iron serum iron below (30 micrograms / dl) (50 - 120 microgram / dl).
And increased rates of total saturation of the iron in the blood (total iron binding capacity (tibc to more than (350 mg / dL) (350 mcg / dl - 250).
And less the percentage of transferrin saturation saturation to less than (15%) (normal = 33%).
Then gradually decreased hemoglobin blood ...
Changes occur in the famous blood red ball, so small-scale pellet microcytic, depigmented hypochromic, and less all amounts to an absolute red ball (the size of the pellet average MCV, mean hemoglobin concentration of MCH, and the concentration of hemoglobin per unit volume of red cell MCHC.
And the last to be affected by iron deficiency is the yeast ENZYM DEPLETION One of the main aspects of vulnerability:
Loss of appetite, anorexia
Agitation irritability
Changes in neurological and psychiatric neurological changes
TreatmentThe ferrous iron salts given by mouth are preferred in the treatment, they are rich in iron, and easily absorbed, cheap, and few side effects. And Mrs. Mubarak: (ferrous sulphate, f.gluconate, f. Fumarate) daily dose (6 mg / kg / day) in three doses after a meal (drops for infants, and syrup for children).Continue treatment until you return to the normal blood data, then add a period (4-6) weeks to fill the empty stores. Affected by the last of iron deficiency (a yeast) is the first to recover with treatment, and is done in the meantime (12-24 hours), with improved appetite, and neurological symptoms fade.
Then begin to improve blood data, and it takes a period ranging from (36 hours) to (month). Becoming more and more cellular bone marrow, and reticulocytes retcs abound in blood circulation, and increases hemoglobin in the blood, and take the red cell characteristics and natural forms.
Then begin the stores empty of fullness, and this is the last stage of treatment, may take (1-3) months.
It remains to say a final word in treatment is that he does not need to give the iron by intramuscular injection, due to the ease of oral administration, unless the patient is so, and if we decided that law of the expense of injection is as follows: the need for total iron (mg) = (the amount of hemoglobin to be submitted × body weight × 3).
Iron is absorbed in the medial part of the small intestine proximal, and specifically in the duodenum duodenum and fasting jejunum.
Factors that help to absorb iron are:
Increase the body's need for it.
Acidity of the stomach.
Vitamin C (C c).
While on the contrary, there are factors that reduce absorption are:
Alkaline pancreatic.
Materials and phosphate.
And all the leading cause of injury to the mucosa of the small intestine, especially the duodenum and the jejunum.
Finally, surgery on the stomach and intestines, which reduces surface absorption.
Iron that is absorbed into the blood, the body is distributed in the following places:
Red blood pigment hemoglobin:
It constitutes two thirds iron body almost, so the loss of blood, and for whatever reason, is one of the most important causes of loss of iron, is enough to demonstrate this fact, recall that each (1 cm 3) of the blood containing the (half-mg) of iron, while (1 cm 3) of the red blood cells containing (1 mg) of iron.
Stores of iron stores:
They are of two types:
Stores moving serum ferritin: a special type of protein, carrying iron and was associated with, the average concentration in the blood (35 ng / ml), and the deficiency is considered one of the most important laboratory signs of iron deficiency.
Stores fixed hemosiderin: The distribution in the liver and bone marrow, and the lack or absence of this article from the bone marrow is the most important and earliest signs of iron deficiency anemia as well.
Serum iron serum iron:
And the range of (50-120 mg / dl = 100 ml) in children, and (70-160 mg / dl = 100 ml) in adults.
Yeasts body enzymes:
Iron enters in the composition of many of the enzymes the body so the shortage is reflected in the work of these yeasts, including:
(Catalase, pyroxidase, mono amin oxidase, cytochrome)
Causes of iron deficiency:The most important causes of iron deficiency in the body are:
Blood loss: We have shown and explained a while ago, so is the menstrual cycle in women of the most important causes of anemia for iron deficiency in women.
Lack of iron contained food: where there is abundance of iron in meat, and vegetables with less in the milk it is very poor (the amount of iron not exceeding half mg in a liter of milk of both types of human and bovine).
Defect in the absorption of the duodenum and the fast (see the factors that help or reduce the absorption).
Clinical picture:Tend to show symptoms of iron deficiency anemia in children yen ninth month to the twenty-fourth month of age. Perhaps the most important signs and symptoms of this disease are:
Pallor: a remarkable and Lecco in the mucous membranes of conjunctivitis, and in the lips, hands and in comfort, and the nail bed. If the progress of the disease shall be pale and clear in all parts of the skin.
Poor appetite
Changes in the skin and mucous membranes
Bite the dust
Magnitude of the spleen (10-15% of cases)
Neurological symptoms and signs: and you see in the cases of chronic and non-treatment (such as jittering and neurological).
Laboratory tests:When there is lack of iron in the body, changes occur in a particular sequence, and the first to be affected are:
Stores: Iron pigment decreases in the bone marrow Hemosidrene or disappears completely, and less protein associated with iron in the blood serum to serum ferritin below (10 ng / mL) = 35 ng / ml) n).
Then the blood hematological changes changes
Decreases in serum iron serum iron below (30 micrograms / dl) (50 - 120 microgram / dl).
And increased rates of total saturation of the iron in the blood (total iron binding capacity (tibc to more than (350 mg / dL) (350 mcg / dl - 250).
And less the percentage of transferrin saturation saturation to less than (15%) (normal = 33%).
Then gradually decreased hemoglobin blood ...
Changes occur in the famous blood red ball, so small-scale pellet microcytic, depigmented hypochromic, and less all amounts to an absolute red ball (the size of the pellet average MCV, mean hemoglobin concentration of MCH, and the concentration of hemoglobin per unit volume of red cell MCHC.
And the last to be affected by iron deficiency is the yeast ENZYM DEPLETION One of the main aspects of vulnerability:
Loss of appetite, anorexia
Agitation irritability
Changes in neurological and psychiatric neurological changes
TreatmentThe ferrous iron salts given by mouth are preferred in the treatment, they are rich in iron, and easily absorbed, cheap, and few side effects. And Mrs. Mubarak: (ferrous sulphate, f.gluconate, f. Fumarate) daily dose (6 mg / kg / day) in three doses after a meal (drops for infants, and syrup for children).Continue treatment until you return to the normal blood data, then add a period (4-6) weeks to fill the empty stores. Affected by the last of iron deficiency (a yeast) is the first to recover with treatment, and is done in the meantime (12-24 hours), with improved appetite, and neurological symptoms fade.
Then begin to improve blood data, and it takes a period ranging from (36 hours) to (month). Becoming more and more cellular bone marrow, and reticulocytes retcs abound in blood circulation, and increases hemoglobin in the blood, and take the red cell characteristics and natural forms.
Then begin the stores empty of fullness, and this is the last stage of treatment, may take (1-3) months.
It remains to say a final word in treatment is that he does not need to give the iron by intramuscular injection, due to the ease of oral administration, unless the patient is so, and if we decided that law of the expense of injection is as follows: the need for total iron (mg) = (the amount of hemoglobin to be submitted × body weight × 3).
ليست هناك تعليقات:
إرسال تعليق