Pernicious anemia is a chronic disease caused by a bug absorb vitamin B 12 (cobalamin) due to lack of intrinsic factor intrinsic factor secretions of the stomach.
And have pernicious anemia in its common accompanied by atrophy of the stomach and loss of production of intrinsic factor, and there are rare cases of pernicious anemia Congenital and where there is a shortage of the factor procedure without the presence of atrophy of the stomach, has launched a label pernicious anemia because this disease was fatal before a cure affordable, and this designation is not appropriate now, but still exist for historical reasons.
Pernicious anemia arises because of the failure of conventional parietal cells of the stomach gastric parietal cells in the production of intrinsic factor is necessary to allow absorption of sufficient quantities of vitamin B 12 from food.
Other factors that affect the absorption and metabolism can cause vitamin B 12 deficiency, which results in macrocytic anemia macrocytic anemia, and neurological complications.
Vitamin B 12 is an organic substance containing metal on an episode of chlorine corrin ring, and the cobalt atom placed the center, and the centrality of different Eginat various axial ligands.- Vitamin B-12 in meat, milk, eggs, and absorbed in a series of steps you need the launch event of the protein proteolytic release of nutrients, and the link protein secreted by gastric parietal cells, known as intrinsic factor.
Identify the complex vitamin B 12 and intrinsic factor by specialized receptors for Vaúfah specialized ileal receptors is necessary for the transition of vitamin B-12 for the session portal portal circulation and the European Union with Baltranzcopalamin 2 transcobalamin II carrier blood serum.
Complex binds vitamin B 12 and Turanczykopalamin cell surface where they are endocytosed within Altqamh to set off the vitamin B-12 liquid cell inside the cell after the dissolution of the complex.
Imbalance with a series absorb vitamin B-12 causes an early defect in infants and children in the form of lack of growth, mental retardation, anemia and large cells.
Pernicious anemia may be an autoimmune disorder autoimmune disorder with genetic predisposition.
The presence of pernicious anemia is more common than expected among the families of patients.
Antibodies to parietal cells are present at 90% of patients with pernicious anemia, and at 5% of normal individuals.
There is a link between autoimmune diseases such as ulcerative colitis, and pernicious anemia.
Vitamin B 12 deficiency may occur because of a lack of quality food, or disorders of the stomach and small intestine, pancreas, and cases of certain contagious, and disorders of absorption, and the food shifts.
It is possible and there is a lack of vitamin B 12 for vegetarians at last for about 5 years and infants of mothers vegetarians.
The main source of vitamin B 12 is the meat and dairy products, eggs, and have need of the body is 1 microgram per day, and stored the body is more than 1000 micrograms.
In adults have pernicious anemia and gastric atrophy accompanied by achlorhydria achlorhydria others irreversible.
Pernicious anemia patients have a risk of cancer of the stomach 2-3 times the normal individuals.Pathophysiology
And have pernicious anemia in its common accompanied by atrophy of the stomach and loss of production of intrinsic factor, and there are rare cases of pernicious anemia Congenital and where there is a shortage of the factor procedure without the presence of atrophy of the stomach, has launched a label pernicious anemia because this disease was fatal before a cure affordable, and this designation is not appropriate now, but still exist for historical reasons.
Pernicious anemia arises because of the failure of conventional parietal cells of the stomach gastric parietal cells in the production of intrinsic factor is necessary to allow absorption of sufficient quantities of vitamin B 12 from food.
Other factors that affect the absorption and metabolism can cause vitamin B 12 deficiency, which results in macrocytic anemia macrocytic anemia, and neurological complications.
Vitamin B 12 is an organic substance containing metal on an episode of chlorine corrin ring, and the cobalt atom placed the center, and the centrality of different Eginat various axial ligands.- Vitamin B-12 in meat, milk, eggs, and absorbed in a series of steps you need the launch event of the protein proteolytic release of nutrients, and the link protein secreted by gastric parietal cells, known as intrinsic factor.
Identify the complex vitamin B 12 and intrinsic factor by specialized receptors for Vaúfah specialized ileal receptors is necessary for the transition of vitamin B-12 for the session portal portal circulation and the European Union with Baltranzcopalamin 2 transcobalamin II carrier blood serum.
Complex binds vitamin B 12 and Turanczykopalamin cell surface where they are endocytosed within Altqamh to set off the vitamin B-12 liquid cell inside the cell after the dissolution of the complex.
Imbalance with a series absorb vitamin B-12 causes an early defect in infants and children in the form of lack of growth, mental retardation, anemia and large cells.
Pernicious anemia may be an autoimmune disorder autoimmune disorder with genetic predisposition.
The presence of pernicious anemia is more common than expected among the families of patients.
Antibodies to parietal cells are present at 90% of patients with pernicious anemia, and at 5% of normal individuals.
There is a link between autoimmune diseases such as ulcerative colitis, and pernicious anemia.
Vitamin B 12 deficiency may occur because of a lack of quality food, or disorders of the stomach and small intestine, pancreas, and cases of certain contagious, and disorders of absorption, and the food shifts.
It is possible and there is a lack of vitamin B 12 for vegetarians at last for about 5 years and infants of mothers vegetarians.
The main source of vitamin B 12 is the meat and dairy products, eggs, and have need of the body is 1 microgram per day, and stored the body is more than 1000 micrograms.
In adults have pernicious anemia and gastric atrophy accompanied by achlorhydria achlorhydria others irreversible.
Pernicious anemia patients have a risk of cancer of the stomach 2-3 times the normal individuals.Pathophysiology
ليست هناك تعليقات:
إرسال تعليق