Known as acidosis Allaktica (lactic acidosis) as a case of systemic to the low pH of the acid decreased systemic pH, which result from the initial increase of hydrogen or decrease in the concentration of bicarbonate, and in the acute situation, the compensation tract of acidosis Allaktica increase breathing hyperventilation, which results in a relative lack of bicarbonate, and in cases the chronic renal compensation occurs through the re-absorption of bicarbonate.
PH increases from increased production of acid and the loss of alkali, or lack of secretion of the kidneys of the acid, and the reason underlying the acidosis metabolic metabolic acidosis can be classified traditionally to the species that increase the gap anion anion gap (AG) (diff positive charges - negative), which does not increase the gap anion , and acidosis Allaktica can be defined as a state of acidity, and high plasma lactate concentration of lactate, a pattern of gap anions, and metabolic acidosis may arise as a result many cases.
The natural concentration of Ktat blood when a patient is not exposed to pressure is 0.5-1 mmol / L, is known to increase lactate blood as a continuously increasing concentration of lactate blood (2-5 mmol / L) without the presence of metabolic acidosis, as acidosis Allaktica is characterized by an increase of an ongoing level of blood lactate, which is usually more than 4-5 mmol / l, with a metabolic acidosis.
Lactate as a product of metabolism Agoi of glucose generated from Alberovi pyruvate in the presence of lactate dehydrogenase lactate dehydrogenase as a catalyst, and Alberovi is converted in the presence of air to carbon dioxide and water in the mitochondria mitochondria in the process of gluconeogenesis gluconeogenesis, and the addition will be Alberovi in equilibrium with lactate, but under certain circumstances can change for the increased production of lactate, and acidosis Allaktica arising from the increase in the level of lactate increases when the production of lactate for consumption, and when the systems buffer buffer systems Body burdened, and it happens when the oxygenation tissue is not sufficient to meet the needs of metabolic As a result of lack of blood flow hypoperfusion or hypoxia hypoxia.
Remove lactate from the blood mainly be by the liver and kidneys (10-20%), as well as through the muscles to a lesser extent, failure CPR cardiopulmonary failure, and sepsis, sepsis, and bruises, traumas, and a lack of vitamin B 1, and the side effect of drugs and toxins, tumors, and many congenital and acquired diseases can lead to lactic acidosis.
Pathophysiology
PH increases from increased production of acid and the loss of alkali, or lack of secretion of the kidneys of the acid, and the reason underlying the acidosis metabolic metabolic acidosis can be classified traditionally to the species that increase the gap anion anion gap (AG) (diff positive charges - negative), which does not increase the gap anion , and acidosis Allaktica can be defined as a state of acidity, and high plasma lactate concentration of lactate, a pattern of gap anions, and metabolic acidosis may arise as a result many cases.
The natural concentration of Ktat blood when a patient is not exposed to pressure is 0.5-1 mmol / L, is known to increase lactate blood as a continuously increasing concentration of lactate blood (2-5 mmol / L) without the presence of metabolic acidosis, as acidosis Allaktica is characterized by an increase of an ongoing level of blood lactate, which is usually more than 4-5 mmol / l, with a metabolic acidosis.
Lactate as a product of metabolism Agoi of glucose generated from Alberovi pyruvate in the presence of lactate dehydrogenase lactate dehydrogenase as a catalyst, and Alberovi is converted in the presence of air to carbon dioxide and water in the mitochondria mitochondria in the process of gluconeogenesis gluconeogenesis, and the addition will be Alberovi in equilibrium with lactate, but under certain circumstances can change for the increased production of lactate, and acidosis Allaktica arising from the increase in the level of lactate increases when the production of lactate for consumption, and when the systems buffer buffer systems Body burdened, and it happens when the oxygenation tissue is not sufficient to meet the needs of metabolic As a result of lack of blood flow hypoperfusion or hypoxia hypoxia.
Remove lactate from the blood mainly be by the liver and kidneys (10-20%), as well as through the muscles to a lesser extent, failure CPR cardiopulmonary failure, and sepsis, sepsis, and bruises, traumas, and a lack of vitamin B 1, and the side effect of drugs and toxins, tumors, and many congenital and acquired diseases can lead to lactic acidosis.
Pathophysiology
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