الجمعة، 3 أغسطس 2012
Hyperthyroidism - increased secretion of the hormone Iierwid
Firas Al Jassim Zarzis
The increase in the secretion of the thyroid gland clinically increase in the amount of hormone Iierwid Thyroid hormone in circulation. It is noted to increase metabolism (the process of construction and demolition in the tissues). Is accompanied by this kind of increase in the secretion of the hormone in the size of enlarged thyroid Goiter. The reasons for this inflation to:
The presence of a foreign body catalyst for Terwid Thyroid, such as who gets the disease Krafess or disease Greif or Gervz Graves disease, a disorder in the mechanism of resistance in the body (immune) autoimmun, and the reason that some bacteria, intestinal, such as E. coli E.Coli has membranes similar to the outer casing for the future of the hormone catalyst for Terwid Thyroid Stimulating Hormone and abbreviated TSH, who shall the body first by attacking the bacteria by T cells T-Cells are immune cells, and then act in the body with any other cell carrying this type of receptors as a foreign body, and thus attack the T cell receptor of TSH , on account of foreign objects, and produces its anti-Anti-TSH receptor antibodies and cells that enter the cystic Thyroid follicular cells leading to secretion Iierwid in large quantities. And can be diagnosed by these antibiotics in the blood of the infected disease Krafess Graves disease. This disease is affecting the eye where it is noted in the eyes protruded exophthamos when infected with the disease.
As a result there are a number of small glands in the toxic thyroid gland, these glands secrete the hormone Iierwid Thyroid hormone through the cystic follicular cells cells located in the lining of the poison glands, most patients with this type of women over fifty years.
Produce large quantities of the hormone stimulating Terwid TSH, and this type is rare
The effects of increased secretion of the hormone Iierwid
Increase in temperature
Increase blood pressure
Palpitations and increased heart rate
Weight loss with increased appetite
Diarrhea and increased movement of the digestive system
Loss of muscle mass
Frenzy
Change in personality
Influence the growth
Discomfort and insomnia
Reduces the work of the ovary in women, and may lead to impotence in men
Lightness of the hair and the strength of the nails with a gloss of the skin
Relationship iodine goiter
There are a lot of iodine in the thyroid gland, which could reach inside to the rate of twenty-five times the rest of the body tissues. A shortage of iodine deficiency in the amount of hormone Iierwid productive, and lead this deficiency to stimulate the pituitary gland pituitary gland to secrete the hormone stimulating Terwid TSH, which leads to goitre, increased blood supply to it by increasing the blood vessels, which leads to increased production of Iierwid hormone.
And the effect of iodine is complex and depends on the given amount of iodine and thyroid status. Can be avoided goiter by eating iodized salt, and by eating fish that contain meat on good amounts of iodine required for the body and absorbed by the body easily.
Treatment of goitre:
Treatment is aimed at reducing the manufacture, reducing the secretion of the hormone overtime, this is done by:
Removal of part or all of the thyroid gland: This is done by surgery or by the destruction of the gland by radioactive iodine I131, which is characterized as an assembly in the bag cells of the thyroid gland Thyroid follicular cells.
Surgery: It is possible to remove part or all of the thyroid gland by surgery, but there is always a risk that affect the process the sound through their effects on the vocal cords, the fact that this gland is located near the vocal cords. In the surgery the surgeon to keep the 8/1 of the gland, and this part is sufficient for the production of Thyroid Iierwid necessary for the body. They are usually resort to surgery for the following reasons:
There is no response to treatment by the patient
The presence of contraindications to expose the patient to radiation therapy
Treatment by radioactive iodine I131: It uses radioactive iodine I131 in the treatment and diagnosis, which accumulates iodine in the thyroid gland, and radiates (shooting rays beta), which penetrates 0.5 mm only in the fabric of the thyroid gland, which provides effective therapeutic modality in the thyroid only without affecting the adjacent tissues such as El Para Terwid Parathyroid. In addition, some I131 radiating gamma rays, which have a greater susceptibility to penetration. The half-life of radioactive iodine I131 is 8 days. And use radioactive iodine I131 in the treatment of hyperplasia of all ages, and is considered as adjunctive therapy with surgery in the case of thyroid cancer. And during treatment with radioactive iodine I131 should be taking a large dose of salts like sodium or potassium would like to help improve the disposal process and directed by iodine from the body. There is a possibility to get from 6-10% of patients treated with radioactive iodine I131 lack of secretion Iierwid Hypothyroid, because of the inability of the thyroid cells to divide again, leading to a lack of Iierwid injury, requiring treatment in this case the patient treatments lack Iierwid Hypothyroid treatment .
Prevent the manufacture hormone Iierwid Inhibition of thyroid hormone synthesis, through one of the following drugs:
Althaioamidz Thioamides
Propyl Theojura_il Propylthiouracil
Methimazole Methymasul
Carbimazole Carbimazole
These drugs are to gather in the thyroid gland, and prevent the manufacture of some important materials that go into manufacturing Iierwid Thyroid. Does not show the effects of fast for this type of treatment, because it does not affect the stock Iierwid, and shows the influence of this type of treatment at the end of Iierwid amount in the body.
Propranolol Propranolol (beta blockers): Used to remove the Links to the symptoms of the disease, caused by increased bad Iierwid, may be used as adjunctive therapy with other types of treatment.
Limit the secretion of the hormone Blockade of hormone Release: type a little use now, and relies on iodine to give a dose to the patient as described, and which to block the release of a substance important in the secretion of the hormone, leading in turn to cut the hormone.
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