الجمعة، 3 أغسطس 2012

Diabetes and cholesterol

The increase in cholesterol in the body very common condition in patients with diabetes (over 70% of patients with type II diabetes have such an increase). And cholesterol is an important factor enters in the composition of membranes of living cells. And plays an important role in the formation of many of the basic materials in the body, including hormones, testosterone and estrogen and progesterone, in addition to being essential in the installation of yellow material manufactured in the liver and stored in the gallbladder, in addition to other functions carried out within the body. But increased cholesterol or any other disorder or defect in the manufactured within the body leads to many problems and serious impact on human health and life. The disorder interferes with cholesterol, many diseases have a direct relationship with diabetes and high blood pressure, cholesterol accumulation low-density (LDL) as well as triglycerides in the arteries, especially coronary artery can cause deadly diseases such as hardening of the artery and myocardial infarction.
So I thought I had said something about cholesterol and its effects and its relevance to both diseases former, diabetes and high blood pressure, because he is one of the reasons that help to get complications, in addition to the methods of treatment without drugs suitable for treatment of the effects of bad cholesterol.
Cholesterol is a steroid substance has the advantages of fat, alcoholic, and hence its name associated with disease, hardening of the arteries feeding the heart. There are several types of cholesterol, but what concerns us two main types of cholesterol and low density (LDL) and call it bad cholesterol "does stick to the inner layer of the arteries feeding the heart", and cholesterol high-density (HDL) and call it good cholesterol "to prevent the accumulation of bad cholesterol on the walls of arteries of the heart. "
High-density cholesterol to total cholesterol is a critical factor in determining the seriousness of total cholesterol in the body to human health. And if the ratio of good cholesterol (HDL) is equal to 0.3 or more total cholesterol (a third of the almost total cholesterol), the sum of total cholesterol is not important in terms of health because the ratio of good cholesterol enough to prevent bad cholesterol from sticking to the arteries of the heart. The ratio of good cholesterol (HDL) natural is 45 mg / cm 3 in males while the figure for females is 60 mg / cm 3, and this explains why the rarity of disease, hardening of the arteries in females compared to males, attributed the reason for this is that the hormone estrogen, which is maintained females in larger quantities than males, according to doctors, is the reason for the high ratio of good cholesterol in the body of women, with evidence that menopause is the point of removal of protection for females with regard to the possibility of exposure to disease, hardening of the arteries, it is known that menopause is the point where you start the process of lack of and diminished secretion of the hormone estrogen in females. And must not be less good cholesterol in the body of 25 mg / cm 3 in males, and not less than 45 mg / cm 3 in females.
Prevention and treatment of high cholesterol

    
Follow a balanced healthy nutrition with the reduction of animal fat (saturated fat) as well as coconut oil and palm oil (saturated oil).

    
Weight loss, whether through sport or diet or both together, and the best combination of the two.

    
Focus on eating complex carbohydrates, as well as foods rich in fiber and soluble in water, such as legumes, vegetables and fruits.

    
Sport continued and appropriate.

    
Control of stress and life's problems.
Drug treatmentThere are several types of drugs used to treat high cholesterol levels and cholesterol Antipyrine called cholesterol-lowering medications or organizations fat Lipid - regulating drugs, which are as follows:

    
Statin Statins:
    
Such as atorvastatin atorvastatin, and Srivastaten cerivastatin, and Vlovastaten fluvastatin, pravastatin and pravastatin, and Smvastatin simvastatin.

    
Be used as a therapeutic first for some types of high cholesterol, the group operates to inhibit the enzyme controls the rate of manufacture of cholesterol in the body called HMG CoA reductase, thus reducing the cholesterol level by reducing the speed of manufacturing cholesterol and increase the ability of the liver to get rid of bad cholesterol in the blood. Usually taken in the evening with dinner or at bedtime to take advantage of the fact that the body produces greater amounts of cholesterol at night. This group is generally safe and tolerable for most patients, and dangerous side effects are rare. Side effects for this group and they get in the muscles, when you get to a doctor should be consulted to replace or reduce the drug dose. This is the best group in the treatment of high cholesterol. This package is suitable for the treatment of diabetic patients with high blood pressure, but must be wary of low blood pressure when standing.
    

    
Viberat Fibrates:
    
Bzafeiberat such as bezafibrate, and Fanovyprit fenofibrate, and Jamephipprozhel gemfibrozil. This group is working to lower triglycerides significantly. And can reduce triglycerides by 50% and raise HDL by 10-25%. The LDL cholesterol may rise or fall depending on the type of disorder that is treatable. Side effects of are: disorders of the digestive system in a simple, there is a possibility that drugs affecting this group of muscle weakness in the muscles Mspbta myopathy. It was noted there are some cases in which drugs interact with this group Groups drugs Asalafohnaal Joris Sulphonylureas, used in the treatment of diabetic patients.
    

    
Exchange resins or resins negative ions Anion-exchange resins:
    
Kolstibol such as colestipol, cholestyramine and cholestyramine. Sometimes called intervals or insulators bile acids Bile acid sequestrates, because it is associated with bile acids in the intestine and prevent re-absorption and that the liver converts more cholesterol into bile acids, thereby reducing the level of cholesterol in the blood. This group is usually described with a statin for some patients with coronary heart disease to increase impact and get a higher to lower cholesterol up to 40%. But there must be a difference between a time period dealt with drugs, because drugs of this group affect the absorption of drugs statin group.

    
Hinder the absorption of drugs of this group of fat soluble vitamins, and that if he continued dealt with for a long time may require the intake of vitamin A, D and k. Have few side effects because they do not usually suck, but it may delay symptoms in the clotting of blood for bleeding due to vitamin K deficiency. Yuhz usually a period of time not less than 4 hours for other drugs in order to ensure the lack of access to interact with other medicines.
    

    
Nicotine acid Nicotinic acid:
    
Such as niacin Niacin. Helps to reduce the level of triglycerides by reducing free fatty acids or free-free fatty acids. This medicine may lead to the high level of sugar because of intolerance to glucose glucose intolerance that the doses are large and may lead to worsening of gout gout. Acipimax property of nicotine acid derivatives is characterized by symptoms with fewer side but is less effective in reducing fat.
    

    
Natural medicines Neutraceuticals:
    
Could benefit the fish oil-rich fish oils with Omega-3 marine triglycerides in cases of high blood fat triglycerides. Believed to stimulate the body to the followers of an alternative path to fat metabolism.
    
Teaching the patientThe responsibility for the patient with all the flags of the return as satisfactory under the responsibility of the doctor, Vaadah most important about these diseases and the meaning of their injury and what the result will be in the case of neglect in addition to the risks of high triglycerides and Alchollstorl.
Must be well aware of the patient that the purpose of giving him this information is not to increase his fears, but hope that the patient is committed to drug therapy and drug to achieve the purpose of treatment.
In addition to the task of the doctor in the treatment of the patient, Valshehadla located it is also a big job in explaining the effect of the drug and its side effects that can appear, and times of taking the drug as well as instructions and the instructions must be provided to the patient, which should focus on medicine as well as to adapt lifestyle to fit with disease and does not conflict with him.
Must always remember that the patient is always in the original treatment, for himself the task of care and the preservation of his health, which is the first person in charge of himself.
The patient not to eat any treatment, drug or drug, without asking your doctor whether this treatment is proportionate to his health. May be of pharmacological therapy interact with medications taken by the patient, leading to lack of access to appropriate treatment or increase the impact of the drug. In case any bidder does not exist already should consult a physician to the possibility that a drug is responsible.
Due to the fact that these diseases have no symptoms, or can be felt by touch, but if levels rose too high. It is necessary to know the patient that the treatment does not have raised the phenomenon can be directly felt by, so the emergence of some side effects, especially at the beginning of treatment, does not mean that treatment is not useful, it should not be less demand for treatment. In addition to attention to the drug not to forget the time or spare medication without consulting your doctor will have serious consequences.
Finally, the patient must remember that these chronic diseases need to be co-existence with them, and lifestyle modifications and adjustment to comply with appropriate healthy living with these diseases

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