الجمعة، 3 أغسطس 2012

Causes of gout

Gout occurs as a result store excess uric acid in the form of salts, uric acid is the end product of purine metabolism of purine metabolism, purine and substance have two sources:

    
The first is food containing this substance as a component of the cell nucleus (such as: animal proteins, and legumes).

    
And the second is the cells of our bodies that contain a substance intentions purine normally.
The bacteria in the intestinal phase of about one-third the amount of uric acid converts it into carbon dioxide and ammonia, as the white blood cells break down a small amount of this acid, and secrete a small amount of it through sweat and get rid of a healthy body is also of the acid excess Bifrazh by the kidneys, When the secretion is not enough to save the blood uric acid level at the lowest level of saturation is 6.8 mg / dl increase in uric acid arise and happen to be crystals of uric acid salts precipitate out the soft tissue. About 90% of patients with gout uric acid salts store because they can not at sufficient quantity excreted through the urine.


May be caused by increased production of uric acid because of genetic abnormalities, or be due to the rapid transformation of the cells as in psoriasis, psoriasis, and chemotherapy for tumors of chemotherapy, or increased consumption of foods rich in Balbaoren may also be a lack of secretion of uric acid due to renal insufficiency, or lead poisoning kidney lead nephropathy, starvation or starvation, and the rapid decrease of weight, or drought, or lack of secretion of the thyroid gland, hypothyroidism, or increased secretion of the parathyroid gland hyperparathyroidism and medications such as diuretics, and cyclosporine (a), or drinking alcohol.

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